Buy MDPiHP Crystal | 4mmcchems – Premium Research Chemical.

Introduction to MDPiHP Crystal

MDPiHP (3,4-Methylenedioxy-α-pyrrolidinoisohexanophenone), also known as 3,4-Methylenedioxy PiHP, is a synthetic cathinone belonging to the pyrrolidinophenone class of compounds. It is a positional isomer of MDPHP, distinguished by the location of the methyl group on the pentanone side chain . Structurally, MDPiHP shares considerable similarity with internationally controlled cathinones such as MDPV and α-PVP .

First formally notified to the EMCDDA in August 2020, MDPiHP has since been identified in seizures across multiple European countries including Sweden, Slovenia, Italy, Germany, Finland, and Austria . The compound is currently regulated in Italy, Lithuania, and Norway .

As a research chemical, MDPiHP is primarily utilized as a certified reference material for forensic and analytical applications. Its detection in biological samples requires advanced analytical techniques, making high-purity reference standards essential for accurate identification . At 4mmcchems, we supply premium-grade MDPiHP Crystal to researchers and professionals worldwide, with a focus on fast, discreet shipping across Europe.

Product Specifications

Product Name: MDPiHP Crystal (3,4-Methylenedioxy-α-Pyrrolidinoisohexanophenone)

Synonyms: MDPiHP, 3,4-Methylenedioxy PiHP

CAS Number: 24622-58-0 (hydrochloride); 749145-17-3 (free base)

Molecular Formula: C₁₇H₂₃NO₃ · HCl

Molecular Weight: 289.37 g/mol (free base); 325.8 g/mol (HCl salt)

Purity: ≥ 98% (verified by third-party HPLC testing)

Form: Crystalline solid

Storage: -20°C for long-term stability

Availability: In stock, ready for immediate dispatch

Chemical Properties and Mechanism of Action

MDPiHP acts as a potent inhibitor of the human dopamine transporter (hDAT), with research demonstrating it is significantly more potent than cocaine at inhibiting dopamine reuptake . The compound exhibits low affinity for the human serotonin transporter (hSERT), resulting in a high DAT/SERT ratio indicative of high abuse potential .

Key Pharmacological Data

• hDAT Inhibition: MDPiHP exhibits 10-fold greater potency than cocaine at inhibiting hDAT

• hSERT Affinity: Low affinity, contributing to the high DAT/SERT selectivity ratio

• Behavioral Effects: In vivo studies demonstrate that MDPiHP produces potent psychostimulant effects, with significant rewarding effects observed even at the lowest dose tested in conditioned place preference assays

• Dose-Response: MDPiHP produces an inverted U-shaped dose-response curve, likely due to the emergence of stereotypies at higher doses

Metabolic Profile

Comprehensive metabolic profiling has identified eleven metabolites in in vitro assays and 22 metabolites in human biological samples. The most abundant metabolite was dimethyl-MDPiHP, followed by dihydro-MDPiHP and hydroxy-MDPiHP . These findings provide essential information for clinical and forensic toxicology, enabling reliable detection of MDPiHP use .

Documented Toxicity

Research has demonstrated that MDPiHP causes lethality at the highest dose tested, underscoring substantial toxicity . Acute intoxications characterized by agitation, tachycardia, and hypertension have been reported .

Why Choose 4mmcchems?

1. Uncompromising Quality

We source our MDPiHP Crystal from certified manufacturers with strict adherence to Good Manufacturing Practice (GMP) guidelines. Every batch undergoes independent HPLC and GC-MS testing to guarantee purity and potency, meeting the ≥98% purity threshold required for analytical reference materials .

2. Discreet and Secure Packaging

Your privacy is paramount. All orders are shipped in plain, unbranded packaging with no external markings indicating contents. Tamper-evident seals ensure security throughout transit.

3. Worldwide Shipping with European Focus

4mmcchems operates a robust global logistics network. We offer fast, reliable shipping to customers worldwide, with a particular emphasis on European markets:

• European Shipping: MDPiHP has been detected in Sweden, Slovenia, Italy, Germany, Finland, and Austria between 2020 and 2025 . It is controlled in Italy, Lithuania, and Norway . We have optimized shipping routes to ensure timely delivery across the continent.

• Fast Transit Times: Typical delivery to European destinations ranges from 3 to 7 business days.

• Tracking Provided: Every order comes with a tracking number for real-time shipment monitoring.

4. Competitive Pricing and Bulk Discounts

We offer tiered pricing for bulk orders, making 4mmcchems the cost-effective choice for large-scale research projects. Contact our sales team for custom quotes.

5. Responsive Customer Support

Our knowledgeable team is available to answer queries regarding product specifications, shipping, and order status. We prioritize clear and prompt communication.

Safety and Regulatory Information

MDPiHP is a regulated substance in several European jurisdictions. The Swedish Public Health Agency has recommended that MDPiHP be added to the national narcotics regulation due to its potential to cause negative public health and social consequences . The compound is currently controlled in Italy, Lithuania, and Norway .

MDPiHP is not currently listed on the 1961 Single Convention on Narcotic Drugs or the 1971 Convention on Psychotropic Substances .

Important Considerations for Researchers:

• Controlled Status: MDPiHP is controlled in several European countries and may be subject to regulation in other jurisdictions. It is the customer’s responsibility to verify the legal status of this product in their jurisdiction before placing an order .

• Research Use Only: This product is intended for research, forensic, and analytical applications only. Not for human or veterinary use .

• Handling Precautions: Standard laboratory safety protocols should be followed when handling this compound. Given its documented toxicity and lethality in research models, appropriate personal protective equipment (PPE) is recommended .

Shipping Information: Worldwide Delivery

4mmcchems is committed to making our products accessible globally. We ship to all major regions, including:

• Europe: All EU member states, UK, Switzerland, Norway, and more.

• North America: USA, Canada, Mexico.

• Asia: Japan, South Korea, Singapore, China, India, and others.

• Australia & Oceania

• South America

• Middle East & Africa

Shipping Methods:

• Standard Air Mail (7-21 days, tracking available)

• Express Courier (3-7 days, fully tracked, signature required)

Customs and Duties: Customers are responsible for any customs duties or import taxes applicable in their country. We provide all necessary documentation to facilitate smooth customs clearance, subject to local regulations.

How to Order

1. Browse Our Catalog: Select MDPiHP Crystal and add to cart.

2. Checkout: Fill in your shipping details and choose your preferred payment method.

3. Payment: We accept cryptocurrencies and bank transfers for secure transactions.

4. Confirmation: Receive an order confirmation with tracking details upon dispatch.

Frequently Asked Questions

Q: What is MDPiHP used for in research?

A: MDPiHP is used as an analytical reference standard for forensic and toxicological applications, including method development for the detection of synthetic cathinones in biological samples such as urine, blood, serum, and plasma .

Q: Is MDPiHP legal to purchase?

A: MDPiHP is controlled in Italy, Lithuania, and Norway, and may be subject to regulation in other jurisdictions. It is the customer’s responsibility to verify the legal status of this product in their jurisdiction before placing an order .

Q: How should MDPiHP be stored?

A: Store at -20°C for long-term stability. Protect from light and moisture .

Q: What if my order is seized by customs?

A: While we take every precaution to ensure successful delivery, we cannot guarantee customs clearance in all countries. Please refer to our shipping policy for more details.